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Aepconia Honiee<Orpantzallan; Tarminolagy; Homerot Nureea Nood Phyalotody: Homeoateale Yaur Frtand10012compares enablaIi4s Vatidbiavanabie...

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Aepconia Honiee<Orpantzallan; Tarminolagy; Homerot Nureea Nood Phyalotody: Homeoateale Yaur Frtand10012compares enablaIi4s Vatidbiavanabie

Aep conia Honiee <Orpantzallan; Tarminolagy; Homerot Nureea Nood Phyalotody: Homeoateale Yaur Frtand 10012 compares enabla Ii4s Vatidbia vanabie



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Subtract. Then check by estimating the difference. $$\begin{array}{r} 224,196 \\ -\quad 98,531 \\ \hline \end{array}$$

Things. Question asked us to compare East African trypanosomiasis with West African trypanosomiasis. So both infections will be caused by this pathogen called Trepagnier Somo Brucie A. However, the pathogen Japan is Soma Brucie. It comes in two different forms we have true Panis Tony Planet Soma Brucie a Gambians which is going to be four hour West African sleeping sickness. And, uh, Japan is so appreciate Road s Ian's for our East African, um, sleeping sickness. So in terms of infection and how the disease progresses, we see that the pathogen will incubate in the blood for approximately 2 to 3 weeks in both cases, but then we see some differences. So in terms of, um, East African trypanosomiasis, this will be overall a much shorter duration of illness, whereas this West African Spanish Sony Asus will be a more chronic form of sleeping sickness. So this is due to the fact that we have central nervous system penetration within a few weeks, um, of the disease infecting the bloodstream. Whereas in West African trypanosomiasis, we see central nervous system penetration 4 to 6 months after infection, or possibly even later. So the disease will. That's progress for several months or up to six years in West African sleeping sickness, whereas the disease is usually over in less than one year in the East African sleeping sickness. And of course, the locations of where these two Panis only uses um, infections occur will be different, so they are going to be common to central Africa. But Western sleeping sickness is going to be in Western Africa, and then East African sleeping sickness is going to be in Eastern Africa. And as far as the infection areas, we see that the Western African sleeping sickness is common to the wetland bio type, whereas the East African sleeping sickness is going to be common to the Savannah bio type. And finally, the transmission in West African trypanosomiasis is going to be human to human, whereas in East African sleeping sickness, we see wild animals to human or possible fecal matter to human. So one is a human human. Where's the other one is going to be zoonotic disease? So overall we see that although there caused by this, how common trip? Ennis Oma Brucie A. We see differences in the West and East African sleeping sickness ease due to the differences in specific um, types of the Sampanis Oma Brucie, a pathogen

Hello and welcome everybody today we will be discussing the differences and similarities between East african and West african trypanosomiasis more commonly known as african sleeping sickness. Now these infections are both native to africa. They are found in the rural areas and they are both parasitic infections caused by this little parasite. Right here, you can see the top of the screen, it's in its end stage of life. This parasite gets passed on from one animal to another. This transmission happens by something called a tsetse fly. When a test flies infected with this parasite, it will typically bite other humans and animals in the area in order to pass it on through its saliva. Now, in order for the infection to properly pass on, the animal usually has to be bitten multiple times, and the amount of flies that are actually infected with the parasite tend to be pretty low. So this is not a very, very common infection preventative measures, measures can be taken, and those that are most at risk are people who are around large swarms of possibly infected flies at a time, such as those that work in agricultural areas or spend a lot of time around cattle or other animals, tourists and other visitors are only at risk if they have extended exposure for the West African strain, it mostly affects humans and it is native to Central and West africa. For the East african strain, it is mostly zoonotic. It only affects animals that we know of, and it is native to East and South East africa. There have been instances where the West african trypanosomiasis has been able to be passed on from mother to baby during pregnancy and childbirth, but it is not a very common occurrence that has been closely documented. Now there is a good amount of symptoms here for this. one. First thing you need to know Is that this disease happens in two stages. The first stage is Hema lymphatic, that means it affects the blood and the lymphatic system. This can cause symptoms such as fever, headache, irritability, fatigue, swollen lymph nodes and aching and sore muscles. Now, sometime later, stage two will happen, which is what happens when the parasite infects the central nervous system. This causes symptoms such as progressive confusion, personality changes, changes in reflexes and motor skills, such as slowness in reaction time or an uneven gait and sleep disturbances, which is why this is known as afghan sleeping sickness as it will usually cause someone to wake up and never be able to complete a full sleep cycle. Now, for the East African strain, the timeline is a bit more acute. It has about a 123 week life and by stage two there is about two weeks in of the infection. The infection site often become swollen and red and can cause pain, which is a big indicator that you have the East African version, which is much quicker. West African is more of a chronic infection. It takes up to three years to be treated and leave the system symptoms may be minimal at first but will become extremely apparent within a few months to a year after infection symptoms need to be addressed during Stage one because by stage two, since it has infected the central nervous system, symptoms can become a bit more permanent and are much harder to treat and or reverse this is why treatment needs to happen. She usually a patient should be hospitalist within Stage One and should be monitored until they have had their blood and spinal tap tested so that, you know, the parasite has left the system. However, there is no preventative vaccine or preventative medication currently available for either strain of this parasite. This does not mean that it is completely non preventable. More physical measures have to be taken for those who are in exposed areas with lots of infective flies. This means that they would need to wear insect repellent, make sure to stay any area, stay away from any areas where the flies could appear such as bushes or stale cars and also wear long clothing that is protective. Long shirt, long pants, hat, as much skin as you can get covered. The fly won't have access to bite you or it will have less area to aim for and there is way to prevent it. Here is just all the information I have put up on the screen so you can take as many notes or anything you want. Um I've had a great time talking to you today And I hope you have a good one.

Hello, welcome everybody Today. We will be discussing the similarities and differences found in East African and West african trypanosomiasis, which is more commonly known as african sleeping sickness. The first thing you are going to need to know is that this is a parasitic infection, which means that a given parasite, the trypanosomiasis parasite will complete its life cycle within a fly, more known as a sexy fly that is common and native in Africa and will then use the fly in order to bite individuals and pass on the disease. However, the number of infected flies in a given population is typically pretty low, so those that are most at risk are natives that spend long amounts of time around the flies and our risk at risk of being bitten multiple times. Tourists and visitors that spend very short amount of times in areas with infected flies have a pretty low exposure rate to this disease. The East African strain can typically be found in the East and southeast portions of Africa, and it tends to be zoonotic, which means it is found to mostly affect cattle and other agricultural animals in the area. The West African strain, very shocking, is found in the central and West areas of Africa, and it is found to mostly infect humans for the West African strain, specifically, there have been instances that we have noticed in which the disease can be passed from mother to baby. However, this is a somewhat uncommon occurrence uh that hasn't been fully documented in a very concise way. Uh Same thing as the disease has seen very few cases in which it can be passed through sex, blood transfusion and organ transplantation, but these cases are very rare and have been poorly documented, which means that we can't exactly say that they are conclusive ways that the disease has been passed on. When it comes to symptoms, we know that the disease has two stages. The first stage is called the he mo lymphatic stage, which means that it affects the blood and the lymphatic system. This causes symptoms such as fever, headache, swollen, lymph nodes, fatigue and aching muscles. This is the stage in which people usually don't realize that they are sick and they might not be seeking treatment because a lot of these symptoms are indicative of other things, such as common cold or other diseases we have seen by the second stage, the parasite has reached the central nervous system and the brain, which is why this is known as a neurological. Let's write that again the neurological stage of the disease. By the time this stage is reached, it is typically fatal without treatment. This includes symptoms such as progressive confusion, personality changes such as a person becoming significantly more irritable changes to reflexes, and motor skills, such as an uneven gait when someone is walking or a decreased reaction time, and the most common symptom that we have seen is sleep disturbances. Typically, people aren't allowed, aren't able to sleep for more than a few hours at a time without having some great disturbance and even when they do sleep, it's not very good quality. So these sleeping schedules are seen to be typically pretty erratic and do not support a very healthy lifestyle specific to the East African strain. We have seen, the timeline tends to be more cute within 1 to 3 weeks. The disease is able to complete its life cycle. The stage two is reached within two weeks and common to the East African strain specifically is infection site pain. So wherever the fly had been, the person, the area typically becomes red, swollen and tender to touch. For the West African strain were able to see that the timeline tends to be more chronic. It is something that a given individual will deal with for a longer amount of time, up to three years, the symptoms appear minimal at first, or they may be erratic in which the symptoms will show up and then we'll go away so the person infected might not realize that they have this disease. However, the symptoms will typically reach reach stage two or become very apparent within a few months to a year after contracting the disease. At this time, there are currently no preventative vaccines or medications available for either strain of this disease. The way in which it can be prevented is through physical measures. So if an individual knows they're going to be in contact with lots of flies or any place where an infected fly population could exist. They would take preventative measures such as wearing insect repellant, wearing long clothing that covers as much skin as possible. They can also stay away from areas in which a fly would sleep or large swarms would stay, such as a car that's been sitting still for a long time or a bush on a really hot day. Those are ways in which we can prevent the disease once the person contracts the disease and they have been diagnosed with it, they need to remain under care of a medical professional until the disease has progressed to a point which they are able to go back to their life until it's completed their life cycle. Um, the diseases life cycle. Thank you for joining me today and I hope you learned a good amount about the trypanosomiasis, uh, infection. And Yeah, have a good one.

We are asked to estimate the falling subtraction and then solve it to get the actual answer. So when estimating, I like to look at the first sets digits on this case. 8 73 and 28 and 73 or 8 73 minus 28. Well, that's going to be equal. Teoh, do this attraction really quick. You take one from the seven to get to six of 13 no equal to five, six miners, two is four and then eight. And that tells me that the answer to the Chevy around 845,000 and then I can check if that answer will be less than or greater than based on the other numbers in the problems in this case, 925 in 744. Now, if 925 was less than 744 that means I would have to borrow from this three in order to subtract them. And since I don't have to, 9 25 is greater than 7 44 That tells me that the answer will realistically be a little above 845,000. So now if we move on with subtraction. We have five minus four, which will be one Tu minus four to his less than force we borrow from the hundreds. Took a to 12. 12 minus four is eights and eight minus seven Is one on then. Here we have 8 73 in minus 28 where we already did that right here. So we know that that is equal to 845. So we guess that the answer would be around 845,000 actually a little above 845,000 and the actual solution ended up being 845,000 181.


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