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Questicn 15 of €0100GC content (9)Which conclusion can be drwn from thadisplayed?The recohinalionincreascs with thc total number of copies of # DNA repeat: Th...

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Questicn 15 of €0100GC content (9)Which conclusion can be drwn from thadisplayed?The recohinalionincreascs with thc total number of copies of # DNA repeat: The dog _ KMIMG GC comtent LbuuL 40R . Laww cumplexity Tpals high reromhinalion rtes Rcpeats (CGACCiJa an CGCCCi)n Have almost identicul recombinatiom rlesMttrat MT:RuluaLutaPalinrLnIhl:-TchUkh GFRDY#uh Uabiliznlia uthcmcmhlmiiFEIHML Grnun73si-0KuluOateira Mole4 ] k Ttin UJ Culcn Cinally-LM Winn | Tnnn LI Hu~lamanfe Rcrion: I2 [cA. "{f

Questicn 15 of €0 100 GC content (9) Which conclusion can be drwn from tha displayed? The recohinalion increascs with thc total number of copies of # DNA repeat: The dog _ KMIMG GC comtent LbuuL 40R . Laww cumplexity Tpals high reromhinalion rtes Rcpeats (CGACCiJa an CGCCCi)n Have almost identicul recombinatiom rles Mttrat MT:RuluaLuta Palinr LnIhl:-Tch Ukh GFRDY #uh Uabiliznlia uthcmcmhlmii FEIHML Grnun 73si-0 Kulu Oateira Mole4 ] k Ttin UJ Culcn Cinally-LM Winn | Tnnn LI Hu~lamanfe Rcrion: I2 [cA. "{f Gencr 10l},94426.+[0059N Fleliln WKMA Majx DeicnWe-ing Mcitic Recumbinaliein Huitint uen . Keutlllzn | Tardal EAAL F KaniL;Gro Lun Suuraln Juu A Khil P; ( _ncrini Qcn RD Gicmrictamhe Tunctioatl BAL Prtscr



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In Exercises $21-24,$ use these results from the "I-Panel-THC" test for marijuana use, which is provided by the company Drug Test Success: Among 143 subjects with positive test results, there are 24 false positive results; among 157 negative results, there are 3 false negative results. (Hint: Construct a table similar to Table 4-1, which is included with the Chapter Problem.) Testing for Marijuana Use If one of the test subjects is randomly selected, find the probability that the subject did not use marijuana. Do you think that the result reflects the general population rate of subjects who do not use marijuana?

Okay, so we're looking at the inheritance of coats in dogs and we have three genes. Helling Waibel curl furnishings. So we can see that long haired dogs have two copies of a long hair gene served longer valuable. Which is receptive to short hair. A little furnishings appear to be dominant. Um And now we have some Russians on it. So at hair length and furnishings waters between type of a long haired dog without furnishings. So it says long haired dogs have two copies of the long hair a little. So that's going to be L L. Because it's recessive. And for the furnishings, jean, we can see that dogs without furnishings are Hamas ideas for no furnishings. So that's going to be again for recessive. Be at Herrington furnishings. What are the genus types of a short head dog with furnishings? Zero multiple possibilities because vega Bieber Hamas, august dominance or hetero sickos at each of these. So perhaps they are gone into all of them like so perhaps they are predominant in the shorter and then you would have this or perhaps its feet away rounds. And you have this all cats. They're hetero sickos in both subversively options. The C We need to be a public square For two heterosexual stocks. So this is going to be like this Minister appoints square. Okay, so what guarantees can we possibly have here from each parent? Well, we can have LF. We can have L. F. Oh or pelvis severa possible gametes for each parent, which is going to be very, very fun stuff around. I couldn't do that. Okay, so to make this easy to read in the actual table, I'm going to use red for dominant and blue for recessive to the first line and let's do some more. So it's gonna be, this makes it a lot easier to read the results. Mhm. And finally just enough. And funny, the ball obsessive. There we go. So quite complicated. If we want to have a look at the radio sir, how many will have dominance in both fruits and be entitled for her And this entire oh down there. So this one and this one. So if I mark the ones will be dominant for both. There we go. There's nine of them. So nine are dominantly growth rates. What about dominance in just the short term? That would be this one and this one And this one served 3. Just dominant with regards to furnishings. That would be this one Swamping this one. So again, three and recessive in both is just this one down in the corner. So we get a ratio of 9-3-3-1.

In this problem, we're going to learn about a practical application of biochemistry and also how studying the genomes of other animals can help us learn more about the human genome. A goal in biochemistry is to be able to treat inherited diseases. These are caused by defective genes or missing jeans. We can treat them by replacing the malfunctioning gene with a functioning version. But first we need to know what Jean does. What an example of a trait controlled by genes is size. There isn't much size variation in adult humans, making it difficult to study. However, there's an uncommonly large size variation for a single species in the domestic dog, ranging from tiny Chihuahuas, two giant Great Danes. It's almost hard to believe that this is a single species, despite the breed differences. Even in a single breed, there can be significant size variation, such as in the Portuguese water dog, which comes in both small in large sizes. Because there's also other morphological differences between breeds, it can be helpful to look at just size in a single breed. So what researchers did with sequence the DNA of a large group of Portuguese water dogs, they then identified the genes that were responsible for the difference in sizes. Next, they looked at an even larger population of dogs with multiple breeds both small and large, and confirmed that the genes responsible for the size differences and the Portuguese water dogs were also difference responsible for the differences in size and the other breeds of dog. These differences in DNA are called single nucleotide polymorphisms, or snips for short. Let's look a little more on the top in blue. We have the sequence for a small dog on the bottom. In green, we have the sequence for a large dog. You can see there's one pair that doesn't match up. This happens consistently among the small and large stock groups. We can identify a gene that's responsible for size differences now, Although researchers did find a single gene that largely seemed responsible for size differences inbreeds, there are also many other genes that affect size, which is why there's different sizes of German shepherds and different sizes of shit suits and different sizes of humans. However, you can see that by studying an animal with a large variation in sizes, it can help us to identify which genes are responsible for size, and then we can apply that understanding to humans and use it to help serve biomedical problems.

Okay, This question asks about comparing DNA bands, and it says the probability for any two random people they're unrelated to have matching band is one of four for any given band. No part A asks us if we compare five bands between strangers. What's the probability that five match so again? To do this, we would need that 1/4 chance for the band to match Tappan five times in a row, which is one in 1024. So we don't have to use the binomial distribution for that one, because there's only one way it could happen. In Part, B asks if the same thing, but for 20 bands. So again we have to have that one in four chance for a band to match happened 20 times in a row. So that's one divided by four to the 20th bill day one in 1.1 times 10 to the 12th so very low. Then Part C says 20 bands. But this time we have 16 or more that match, and for this one we want the probability that X is greater than or equal to 16. But that's the same thing as one minus the probability is we don't want, which is X is less than or equal to 15 because we want 16 17 18 19 and 20 which means we don't want zero through 15. And I just did this so we can use our binomial CDF function in a case where we have 20 trials, a 1/4 success rate and you want the matches between zero up to 15 and this is converting to a fraction approximately one in 2587 111 and Part D asks if two people take a paternity test and 16 or more bands match. Should you believe that the two people are related, father and son And yes, because because one in that approximately 2.5 million those are pretty good arts for just a random stranger.

This time, I want to find the probability off the subject either testing positive or not using marijuana. So subject testing positive is 1 43 by 300 1. 43 by 300 by 300 or or means addition. Not using marijuana, which is the addition of these two 24 plus 1. 54 is 1 78 by 300. Is that Is there something common? Yes. This is the intersection part minus 24 by 300. So what does this turn out to be? This turns out to be 0.99 So this is the probability that I want 0.99


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