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Why cun the reactions of glycolysis simply be run in reverse t0 synthesize glucose? Explain how this problem is overcome in gluconeogenesis....

Question

Why cun the reactions of glycolysis simply be run in reverse t0 synthesize glucose? Explain how this problem is overcome in gluconeogenesis.

Why cun the reactions of glycolysis simply be run in reverse t0 synthesize glucose? Explain how this problem is overcome in gluconeogenesis.



Answers

How are the irreversible reactions of glycolysis bypassed in gluconeogenesis?

Explanation for the question because it would not be and then said people leave possible and possible sins. It is highly injured. Gunning the tree reaction have find negatively standard free energy changes in the black alighted direction. In addition, if these similar enzymes are to be used for all the reactions, But I could laces and glue glucose new Genesis, then it would be impossible to control board processes independently.

Discussion wants to know why glucose can't be synthesized by glycol sis reactions running in reverse. So the so glad callouses is a favorable eggs. Organic reaction. Um, with a delta gee of negative 90 killer jewels. Permal while the reverse of like Hollis iss is on undergone IQ reaction with a delta G of positive 90 killer jewels per mole. Um, and this makes the reverse of, like, Hollis ists to produce glucose unfavorable to take place.

Okay, so here we have kind of just accrued equation of, um, glycol ASUs. So we're taking glucose, and we're breaking it down into Piru Lake and are actually making two pi relates, but that's not important. Um, what is important is that we know this reaction has a negative delta G value. Um, and when a reaction as a negative delta G value, that means that the reaction is spontaneous. So that means it'll just occurring on its own. It's energetically favourable. Um, what we also know is that if we have a reaction se x y, um or ex going to why and the forward reaction the Delta G is negative. We know that the, um oops, it's a little messy. Here we is negative. We know that the reverse reaction must have a Delta G. That is positive. So if Glad Colossus was just the reverse, Or if Falconio Genesis was just the reverse of glycol ASUs, it would not be energetically favor because it favorables because it would just be the reverse reaction. So the reaction wouldn't be able to proceed since it's not energetically favourable. So in order to get around this, um, we use different steps in order to get back, um to glucose without using the same exact pathway in order to

Book a Gun. She is a messenger released by the liver increases the production of new glucose through co neo Genesis. And it does this by lowering protect us to six this boss F to 60 for short, which Alistair Eric Lee activates increase Google neurogenesis.


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