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Subjects with pre-existing cardiovascular symptoms who were receiving subitramine, Ppetize suppressant, were found to be at increased risk of cardiovascular events ...

Question

Subjects with pre-existing cardiovascular symptoms who were receiving subitramine, Ppetize suppressant, were found to be at increased risk of cardiovascular events while taking the drug The study included 800 overweight or obece subjects with pre-existing cardiovascular disease and/or type diabetes_ The subjects were randomly assi ined to subitramine (4903 subjects placebo (4897 subjects) double-blind fashion; The primary outcome Measurec was the occurrence of any of the following events; nonfa

Subjects with pre-existing cardiovascular symptoms who were receiving subitramine, Ppetize suppressant, were found to be at increased risk of cardiovascular events while taking the drug The study included 800 overweight or obece subjects with pre-existing cardiovascular disease and/or type diabetes_ The subjects were randomly assi ined to subitramine (4903 subjects placebo (4897 subjects) double-blind fashion; The primary outcome Measurec was the occurrence of any of the following events; nonfatal myocardial infarction or stroke, resuscitation after cardiac arrest, or cardiovascular death_ The primary outcome was observed in 591 subjects in the subitramine group and 473 subjects in the placebo group_ (a) Find the proportion of subjects experiencing the primary outcome for both the subitramine and placebo groups_ (Round your answers to three decimal places ) Ptreatient pulacebe (b) Give 9590 confidence interval for tne difference between the proportions of subitramine and placebo subjects who experienced the primar outcome, (Use Psubltramlne Pplacebo Use the plus four method Round your answers to three decimal places,)



Answers

Numerous studies have shown that high blood cholesterol leads to artery clogging and subsequent heart disease. One such study by D. Scott et al. was published in the paper "Plasma Lipids as Collateral Risk Factors in Coronary Artery Disease: A Study of 371 Males With Chest Pain" (Journal of Chronic Diseases, Vol. 31, pp. 337- 345). The research compared the plasma cholesterol concentrations of independent random samples of patients with and without evidence of heart disease. Evidence of heart disease was based on the degree of narrowing in the arteries. The data on plasma cholesterol concentrations, in milligrams/deciliter (mg/dL), are provided on the WeissStats CD. Use the technology of your choice to do the following. a. Obtain a normal probability plot, boxplot, and histogram of the data for patients without evidence of heart disease. b. Is it reasonable to apply the $t$ -interval procedure to those data? Explain your answer. c. If you answered "yes" to part (b), determine a $95 \%$ confidence interval for the mean plasma cholesterol concentration of all males without evidence of heart disease. Interpret your result. d. Repeat parts (a)-(c) for males with evidence of heart disease.

Let us look at this question. So over here to descend that the interviews or videotape and studied to assess the emotions off the individuals, the researchers determined the determined which individuals in the study experience any type of heart disease over a 10 year period. So this is what we can say a prospective type of a study. So since this is, you know, this study lasted for such a long time, this is going to be a cohort study. Right? This is going to be a cohort. Study. Now, what are these? These are, you know, the studies where first a group is identified to participate in the study and then they are observed over a long period of time, and then the characteristics are recorded and then the studies continue. So this is a cohort study. The second question is what is the response variable? What is going to be the response variable? The response variable in this case is they are trying to, you know, see if there is an association between the level of happiness and their risk, their risk of heart disease. So the response variable is the risk of heart disease and the splendid variable is whether the person is happy or not. That is the level of happiness. In the report, the researchers stated that the research team also hasn't ruled out ruled out that a common factor like genetics, could be causing both the emotions and heart and the heart disease. So this looks like a lurking variable, right? This looks like a looking variable and these would be my answers.

Let us look at this question. The researchers studied 17 39 people over the course of 10 years. Now, over the course of 10 years, this looks like a prospective study. So this is a cohort study, right? A cohort study. Okay. During this 10 year period, they interviewed the individuals and ask questions about their daily lives and the hassles they face. In addition, hypothetical scenarios represented and so on and so forth. Let us simply move to the questions. What type of observation city is this? This is a court study. Okay, so what is the response Variable now, in this case, they're also asking what is the response variable? Okay, the response variable is whether they have a heart disease or not. Okay, Whether they have a hard disease, whether they have a heart disease or not, this is going to be my response. Variable. And what is the Xfinity variable If they are happy or not? My excellently variable is if they are happy or not, right? Let us move on toe, see various questions. Okay. The researchers stated that the research team also has hasn't ruled out that hasn't ruled out that a common factor like genetics, could we? Causing both emotions and heart disease. What does this sentence mean? Okay, now what does this sentence mean? It is quite possible that there is confounding due to lurking variables. This sentence implies that there is confounding, uh, due to looking do toe knocking variable. This is my answer.


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