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What does DNAse hypersensitivity refer to? Mitotic chromosomes 8 DNA that is bound to histones Facultative heterochromatin DNA that can be accessed by DNAse [ Whar ...

Question

What does DNAse hypersensitivity refer to? Mitotic chromosomes 8 DNA that is bound to histones Facultative heterochromatin DNA that can be accessed by DNAse [ Whar is the approximate diameter of a nucleosome particle? nm 10 nm 50 nm 100 nm

What does DNAse hypersensitivity refer to? Mitotic chromosomes 8 DNA that is bound to histones Facultative heterochromatin DNA that can be accessed by DNAse [ Whar is the approximate diameter of a nucleosome particle? nm 10 nm 50 nm 100 nm



Answers

Assuming that the 30 -nm chromatin fiber contains about 20 nucleosomes $(200 \text { bp/nucleosome) per } 50$ nm of length, calculate the degree of compaction of DNA associated with this level of chromatin structure. What fraction of the 10,000 -fold condensation that occurs at mitosis does this level of DNA packing represent?

This question asks, What is the axial ratio of a 20 micro meter long DNA molecule? So the diameter of DNA is known to be 20 angst Rome's, which is equivalent to 0.2 micro meters. And we know from the question that the axial ratio is given by dividing the length of the DNA molecule by its diameter, and we know the length to be equal to 20 micro meters. I was given by the question and now we know that the amateur is 0.2 micro meters, so we should find that the axial ratio for this molecule DNA is equal to one times 10 to the four.

So the exact ratio, that is the length to diameter of 20 micrometers long DNA molecules should be determined. So in science, a rod like molecules are named as actual ratio. In normal language, it is the length of the road, whatever the diameter of the john. So uh unit of special measurement that it goes to one billion of a meter. Human hair is about 60,000 nanometers in diameter. Well, a violent dial on DNA molecule is between 2 2000 nanometers. White in an echo isolation. The average persistent length is 46 to 50 nanometers or 1 20 to 1 40 to 1 50 days pairs. So the diameter of DNA is to nano matter, although it can be very significantly. We typically use on stone or one arm storm is equal to 0.1 nanometer and 3.4. One always a good 2.1 nano meters and 3.4 armstrong and one full of full loop of the headaches have about them. Based there also one micrometer is occur 2000 nanometer. And the diameter of the DNA is diameter. Oh, state DNA, He's 20 and stone. And do you know one of you on this point one nanometer? So the diameter of the uh DNA is wine to nano meters. And also this is because uh one like this is because one micrometer is equal 2000 nanometers and the length is and the length. He's 20,000 nanometers. So so the exhale ratio yes 20,000 upon to there is a girl too. And because of.

Care for the solution. For the step plan. The stones are alkaloid protein present in eukaryotic chromosomes. They are positively charged and bind to negatively charged DNA. This his stones can be considered as the chief component of cremating. No, the isola click point of his turn, Proteins is considered to be very high around 10 0.8 I saw electric point refers to the ph at which The neck charge of molecule becomes zero and the molecule is electrically neutral. The high P. I. Of stones, such as that. They are composed of positively charged amino acid residues. Does the amino acid residues that must be present in relatively large numbers in his stones would be lacing history and urgent in now For the step two amino acids are the monomer units of proteins. These are basically organic compound consisting of carbon, Zelic group and amino group along with this functional group, a side chain. Our group also present in all the amino acids. Now the positive charge present on amino acids helped the histone residue is to bind to negatively charge DNA. This is how the amino acid contribute to a strong binding of the stone to DNA through icon ionic interactions. So this is a complete solution. With the introduction and explanation. Please go through this.

From here asked what a nuclear zone is, So a nuclear zone here is going to be the basic structural unit of DNA. Um, packaging. Essentially, they basically art there unwrapped, rocked by the function of his stones, which basically help in the expression of various genes. So this last question here as how our nuclear dooms arranging condensed 39 amino five meter fibers rather and they do so by wrapping itself up with hissed owns.


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