## Question

###### Rank the following species in order of their strength as nucleophiles CH3O CF3CHzo' For each pair of compounds_ circle the better leaving group: HO or HzO CH;SO3 or CF3SO3 F or Br" CH3SO3 or Br CHzO" CH3COz" For each pair of compounds, circle the better nucleophile: NHz or NHz CH;o" or CHzs HC C or N=C Cl or | HO in ethanol vs HO in diethyl ether CH;OH vs (CHs)COH PhCHz vs CHzCHz" Provide reasons for why the molecule you selected for each has the faster Sn2 rate E2

Rank the following species in order of their strength as nucleophiles CH3O CF3CHzo' For each pair of compounds_ circle the better leaving group: HO or HzO CH;SO3 or CF3SO3 F or Br" CH3SO3 or Br CHzO" CH3COz" For each pair of compounds, circle the better nucleophile: NHz or NHz CH;o" or CHzs HC C or N=C Cl or | HO in ethanol vs HO in diethyl ether CH;OH vs (CHs)COH PhCHz vs CHzCHz" Provide reasons for why the molecule you selected for each has the faster Sn2 rate E2 rate t-Bu t-Bu" CH3 t-Bu t-Bu" CHa CH; CH;

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