## Question

###### Cl /HCO} antiporerGhanneHCO,HCOgchannelCorbinic enhyin?H/KT APaseADP HzoCozCOz+OHBasolateral membraneApical membraneTight junctionJondoedStomih lmcn FH 1-OPH .-pK 2FIGURE 11-31 Acidification of the stomach Iumen by parietal cells in the gastric lining: The apica) membrne parietal cells con Lains /K" ATPase ~class pumpi well = andk' chunnels Note the cyclic K transport across the apical membrane: Jons are pumped Inward by theH" ATPase and exit via J channel The basalateral membran

Cl /HCO} antiporer Ghanne HCO, HCOg channel Corbinic enhyin? H/KT APase ADP Hzo Coz COz+OH Basolateral membrane Apical membrane Tight junction Jond oed Stomih lmcn FH 1-O PH .- pK 2 FIGURE 11-31 Acidification of the stomach Iumen by parietal cells in the gastric lining: The apica) membrne parietal cells con Lains /K" ATPase ~class pumpi well = andk' chunnels Note the cyclic K transport across the apical membrane: Jons are pumped Inward by theH" ATPase and exit via J channel The basalateral membrane canlainsJn Jnion antiporter that exchanges HCO; andCi ions- The combined operatian of these four different transport proteins and carbonic unhydrase acidifies the stomach lumen while maintaining the neutral pH ol the Cytosal

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