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# 8. (2 pts) In Drosophila dorsoventral patterning, cactus encodes the protein that holds the Dorsal (DI) transcription factor in the cytoplasm thus preventing its nu...

## Question

###### 8. (2 pts) In Drosophila dorsoventral patterning, cactus encodes the protein that holds the Dorsal (DI) transcription factor in the cytoplasm thus preventing its nuclear localization: Remember that Dl is localized in a nuclear gradient with highest levels in the ventral region, and is required for ventral cell fates. cactus is degraded upon phosphorylation by the pelle kinase after Toll receptor signaling; spatzle is the Toll ligand. What would be the phenotype of embryos derived from a female h

8. (2 pts) In Drosophila dorsoventral patterning, cactus encodes the protein that holds the Dorsal (DI) transcription factor in the cytoplasm thus preventing its nuclear localization: Remember that Dl is localized in a nuclear gradient with highest levels in the ventral region, and is required for ventral cell fates. cactus is degraded upon phosphorylation by the pelle kinase after Toll receptor signaling; spatzle is the Toll ligand. What would be the phenotype of embryos derived from a female heterozygous for a Toll dominant allele that makes a ligand- independent receptor (active everywhere along the dorsoventral axis) and homozygous for a spatzle loss of function allele with respect to: the cuticular pattern dorsalized or ventralized (circle the correct answer) the subcellular localization of the dorsal (DI) protein in the ventral region nuclear or cytoplasmic

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