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37. What chromosome aberration do individuals with familial Downsyndrome exhibit?Multiple ChoiceChromosome 21 duplicationChromosome 14 trisomyChromosome fusion invo...

Question

37. What chromosome aberration do individuals with familial Downsyndrome exhibit?Multiple ChoiceChromosome 21 duplicationChromosome 14 trisomyChromosome fusion involving 14 and 21Reciprocal balanced translocation between chromosomes 14 and 21

37. What chromosome aberration do individuals with familial Down syndrome exhibit? Multiple Choice Chromosome 21 duplication Chromosome 14 trisomy Chromosome fusion involving 14 and 21 Reciprocal balanced translocation between chromosomes 14 and 21



Answers

What type of chromosomal abnormality leads to the phenotype known as Down syndrome?
a) trisomy 21 b) monosomy 21 c) monosomy 22 d) trisomy 22 e) disomy 21

What causes down Sandra. And, uh, what is down syndrome is a genetic defect. The individuals have extra copy of chromosome 21. I'm so he was are deployed. That means they have 23 pairs of home, a homologous chromosomes. Now it harmonicas chromosome have two copies. One copy from Mom. The other copy from debt. Now the individual who have an actual copy of chromosome number one, um, caused by none. Disjunction has three copies. So that's why we called it truck trisomy 21. So the individuals who have down syndrome usually have similar symptoms, including delay development, learning disabilities just at you. And they usually have certain facial features, including a flexible phase, especially the bridge of the nurse, almost in eyes that slant up a short neck. And this more years

Hi there. Um, we're looking at chromosomes in humans. The normal deployed number. Of course, that is referred to as to end the normal deployed. A number of chromosomes and humans is 46. There are 22 pairs of auto zones. Do those are the non sex chromosomes? And then there's one pair of sex chromosomes that determine whether the offspring it's a male or female with X X being female and X y giving you a male. Alright. But for this question, I want to focus on these 22 pairs of auto zones. They could be arranged. You could take a photo of them, have enlarged the photo and cut out the actual chromosomes and arrange them in order of decreasing size that is called a Correa type. When a Correa type is done, the largest chromosomes come first, and then they go in decreasing order. So chromosome number 21 is one of the smallest chromosomes, right? Okay. Logic tells us that the smaller chromosome is the fewer genes it contains. Um so tries Ilmi. Yeah. Refers to an instance where there are three copies of one of the chromosomes rather than the normal two copies so Down syndrome is caused by three copies of the number 21 chromosome. And this question is asking about why there are more individuals with down syndrome than those that are tries. Oh, me three or tries. Oh, me for number 16, In other words, have three copies of these, and a good explanation of this is what we said about the chromosomes being numbered from largest down to smallest and that smaller chromosomes are going to contain fewer jeans. Chromosome number three is one of the largest chromosomes, so it's logical to believe that it would contain the most genes or more genes than most of the other chromosomes. Even chromosome number 16 is considerably larger than chromosome number 21. So it is believed that if you have three copies of these that contain Mawr jeans, it is more likely to have a lethal outcome. Okay, so cool. Okay, thanks. Individuals that are tries only three or tries only 16 most likely are miscarried during the pregnancy due to having an extra copy of these much larger chromosomes and therefore an extra copy of many more genes. So, looking at our answer choices here, um, it looks like Letter D is going to be our correct option because Letter D says that extra copies of the other chromosomes are probably fatal because they do contain more G. There are larger, they do contain more genes, and they most likely cause a fatal outcome. So Letter D is the correct answer. Thank you for watching.

So the impact of an extra chromosome isn't air that occurs during cell division. So you have your cunt normal cells that divide normally where you have to and then you haven't error. That occurs where the cells divide and there's actually three. So that's it. A mistake that's happening during cell division. And if sells three or 16 or any other cells resulted in this extra chromosome, it might be so harmful to development that it would result in a fatality, Um, and so the the child would not be born. An extra chromosome in 21 problems on 21 has a less drastic impact on the genetic balance, and therefore, um, is more common in the population.

Hello, everybody. This is Ricky. And today I'm gonna be walking through a problem 37 from chapter 10. And in this question, were given a carry, a type and looking at the carrier type, we have to determine non destruction in which of the chromosomes cause down soon so we can look, um, each of the chromosome numbers looks fine. Until we get to 21 here, we can see that there's a trisomy, uh, particular trisomy 21. Um, and non destruction Here lead Thio a three crow motives. Um uh, leading to, ah, an extra chromosome where there should not be one. So our answer would be a chromosome 21 is where the non destruction occurred. So this video's help


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