Hi, My name is Priya, Mona's and I will be answering my interview question. So this question consists of two parts. The first part, part A is dealing with patch clamp diagrams. So four patch clamp diagrams the peaks that we see something like this shows that the ion channel ion channel is open and when we do not see a peak, that means the ion channel is closed. So if we're looking at the figure, we can actually see two distinct channels based on the differences in current. So the 1st, 3rd and last peak, which are kind of bigger are approximately equivalent. So we can say that that is one ion channel or one distinct type of ion channel. In contrast, the 2nd, 3rd or the second and middle three peaks are also approximately equivalent. But they're a lot smaller and so we can conclude that this is also a separate but one type of ion channel. So in conclusion, we have two distinct ion channels based on our patch clamp diagram. Alright. So Part B is actually looking at how maney ions cross the open ion channel within one millisecond so part me, and were given a lot of helpful information. So for this question, we actually need to know from the patch clamp diagram how much current is flowing through these two distinct channels and were given a pretty helpful legend. So the legend says that about one third of the larger peak is too fecal lamps. So if it's one third, then the larger channel is likely, or PICO amperes is likely going to be six PICO and pierce for the larger channel, the smaller channel looks to be about double the amounts of are given legend. So we can say that this current is likely for PICO and Pierce, so knowing that we can move on to the givens provided in the question. So the first given is that we know one ampere is equal to one cool, um per second. That's our first given on, then the second given is one. PICO and peer is equal to 10 to the negative 12th amperes. All right, and then next we know that sodium is going thio, so our sodium ion is going to carry a charge of 1.6. Let's see, 1.6 times 10 to the negative 19th columns. All right, So what does this all mean? And why do we care? So we know from earlier that I can show up Here is we have different currents, right? We have four PICO amperes for one and six PICO amperes for the other. So for four PICO em peers, we need Thio convert it to amps. Right? So are just amperes, right? So how do we do that? We multiply four PICO amperes by one times 10 to the negative, 12th and pierce And then this way over one peek a lamp. Here we can cancel out our PICO in Pierce and we are left with four times 10 to the negative, 12th and Pierce. Okay, so we're just going based off of are given here. Next, we want to convert our amperes into columns. So using our first given, we're going to do for times 10 to the negative. 12th Can pierce. And we're going to do times one cool own per second. And so we are going to get we can cross out our amperes and we're going to get four times ton to the negative 12. Cool. OEMs per second. All right, so now we have that now we need Thio Move on to our last given, which is feeling with our sodium ions. So we know that one sodium ion is 1.6 times 10 to the 19th columns. So we take our four times 10 cool ums per second and we multiply that by one sodium ion from which is what were given 1.6 times 10 to the negative 19th columns. So here we can cross out our columns and we're left with 2.5 times. Yeah, let's see times 10 to the seventh, sodium sodium ions over one second. Okay, but the question is asking for ions per millisecond. So our last step is to just multiply this by one second over 10 to the three milliseconds. Uh, so if we do this 10 to the three milliseconds, we get to 0.5 times 10 to the fourth ions her one No, a second. Okay, so we follow the same pattern, remember for our other channel here for our six PICO am's. So PICO amperes. So going on here, getting some room, we're going to start with six PICO amperes. We're gonna multiply this, remember, we have to convert to amperes times one times 10 to the negative. 12th and piers over one PICO ampere. Next, we have to convert to columns over second over second. So remember, that's pretty easy. It's just one. Cool. Um, for a second, then we're gonna multiply this. We have to convert the ions, so we're gonna have one sodium I on over 1.6 times 10 to the negative 19th. Cool on. And we can go back and make sure that our units are canceling properly. Right? So we cancel our PICO amperes, we're left with amperes. We cancel our cool ums so we're left with, uh, we're gonna be left with our Dampier's and our ions over seconds. But remember, we still need to get to milliseconds. So we're going to dio times one second over 10 to the third milliseconds, and so we can cancel our seconds out. Okay, so now that we have all of this, if we multiply through, we're left with three 0.8 times, 10 to the fourth. And this is going to be sodium ions. I'll just put it here over not seconds.