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MHC and mate choice. How can individuals detect each other’s MHChaplotypes? Why is MHC diversity important? You can alsothink about MHC diversity outside of ...

Question

MHC and mate choice. How can individuals detect each other’s MHChaplotypes? Why is MHC diversity important? You can alsothink about MHC diversity outside of mate choice. For example, howdid MHC diversity play a role in the susceptibility of Indigenousgroups exposed to smallpox virus by Europeans in the New World?Discuss.

MHC and mate choice. How can individuals detect each other’s MHC haplotypes? Why is MHC diversity important? You can also think about MHC diversity outside of mate choice. For example, how did MHC diversity play a role in the susceptibility of Indigenous groups exposed to smallpox virus by Europeans in the New World? Discuss.



Answers

What is the function of the MHC antigens? Why are the genes that encode these antigens so variable?

All right. Today's question is a little bit more quantitative. So we're gonna be talking about, yeah, the response to selection related to narrow sense heritability and the selection differential. What information does the response uh selection provide? So we're going to say is the uh response to selection it's going to be our is equal to each to times S. So H. two is the narrow sense heritability, hair, hair ability and s. Is the selection differential? So the value of our predicts how much the mean quantitative genotype will change with different selection in a single generation. That's basically it for this video have eyes A.

For this question. We're looking at the role and function of MHC two molecules. So here we have to distinguish between MHC one and MHC to first of all, so M H. C one is the primary major history compatibility complex components, and it's for recognizing intracellular antigens, and this will be found in all cells. MHC two is for extra cellular antigens, and this is only found typically in your professional antigen presenting cells such as your macrophages or your B cells, per instance. So how this works is you have your cell and you have an antigen. On the outside of that self, your auntie gin presenting cell is going to fade. Mosquitoes the androgen and bring it into the cell. So here you have the cell with the anti gin on the inside of the body. It's going to digest this auntie gin or bacterial component into base er, amino acid strands and other simpler proteins that combined better to our MHC complex. So here you're going to degrade it into proteins, and these proteins are going to bind to the MHC too complex found on the inside of the cell. It's going to bind and fuse together, and it's going to move to the surface of the cell. So here you would have the MHC molecule on the outside with those amino acids antigens being presented. And this is going to interact with, say, your T helper cells or other antigen presenting cells in order to facilitate a response for the production of antibodies or for CIDA toxic interactions to destroy cells or extra cellular components that contain these, such as bacteria. So here, the main takeaway point is that MHC two molecules work on extra cellular components by bringing them in, processing them into smaller amino acid sequences and binding them to an MHC two molecules and migrating back to the surface of the cell. Or they'll then interact with T helper cells or, say, a piece sell to induce an immune response.

So hello, students and discussion. We have to learn genetic diversity, responsibilities for evolution process. And we all know that evolution is the Onley thing that brings difference presses is different type of organisms in the world. OK, so evolution Uh, that means that the behavioral and physical changes in especies according to the environment and it depends on different factors. But here we concerned about the genetic diversity. So what genetic diversity means genetic diversity is is that the submission or total number off genetic characteristics present in a species, Yet we door three type of lines. Okay, so the green line is off time. That means the time progress in this direction. The red line represents the genetic diversity. That means when the time become progress and the environmental changes negligent, then genetic diversity. That means the variation in genes are less when the times increases and the blue line means the population size. So when the genetic diversity is constant, then population size always increases because there will be no changing environment. Maybe there is a change, but there is. The change is negligible. Okay, but one thing you have to understand that no environment, any environment is changeable. That means it is not a constant. Okay, That means the environment becomes, um, hotter, colder dryer, basic acid. And there are several catastrophic effects in a environment. So these 10 years air there. So why genetic diversity? Because we have always know that there are two types off animal. One is the sexual animal on another is their sexual enemy. So as sexual animals who do not have their genetic diversity because they are a sexually produced and obviously there will be no genetic variation in a sexual animals, so are sexual animals does not suffer in evolution of genetic diversity. But the sexual animals, because they sexually reproduced and their variations are genetically so obviously they can, uh I mean, not all the species that means all of the animals in the species are survived because there is a changing environmental. Some off them are obviously vary it their genes and regulate their activities according to the environment and survived. So this is the actually

Look, buddy, this is Ricky. And today we're gonna work. Walkthrough problem 31 from chapter 33. All right, so say we have a little guy home. Steve and Steve needs a new torch. The only problem is that cardiac cells on the new heart have thes, um, agency one complex. Are these m A C one proteins that Steve does not have? So why is this a problem? Well, this is a problem, because natural killer cells see foreign M A C one proteins, and I think that a virus is invaded. And so they worked on the tackle. So eight garnets. This video is helpful.


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