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Provide a brief (no longer than three sentence) description of how cortisol elicits a response within a target cell....

Question

Provide a brief (no longer than three sentence) description of how cortisol elicits a response within a target cell.

Provide a brief (no longer than three sentence) description of how cortisol elicits a response within a target cell.



Answers

Part of cortisol's role in the body involves passing through the plasma membrane to initiate signaling inside a cell. Describe how the structures of cortisol and the plasma membrane allow this to occur.

The question, we're wondering what role does cortisol play in response to the initial, you know, the stress, Right. What kind of role does it play? An initial stress response? So it kind of mapped out a little bit of a pathway here to give you guys a sense of understanding in terms of how critical functions, right? Where it kind of comes into play. So let's say we have this just a similar circled up here. What happens is is going to force the hypothalamus to release C. R. H. Right. CrH is going to go ahead and bind to the interior pituitary, which is directly underneath that effectiveness. And then that's going to release its own kind of thing. A see th A. C. T. H. Is going to go ahead and bind to the original plans directly above the kidneys. And that in turn is going to release what is called cortisol, which is what we're curious about. So what does cortisol do? Well, cortisol is very important in what is called the flight or fight response. Right? So cortisol is very, very important and basically getting our body in such a state that we can react to that initial stimulus. We can, you know, run away from it. Or we can we have enough resources in our body that allows us to react to this stressful stimulus. In an effective way. An example would be, for instance, your blood pressure going on right. Your body would be really, really trying to get the blood flow pumping because it needs to let the oxygen circulate various parts of your body. You need energy right to be able to escape the stressful situation. That's really the easiest way you can think about it. So that's really the real cortisol place here. And you might be wondering, okay, well, how do we shut that off? Right. We don't want to always have super high blood pressure or we don't always want to be in flight or fight mode. Well, it's pretty easy, right? We kind of see this feedback pathway what cortisol ends up doing. And I'm going to actually draw in a different color here is going to go ahead and really affect a different part of the brain called the hippocampus, right? And it's going to basically allow this kind of pathway to be able to shut down so that this flight or fight response mode isn't continually active.

We want to describe three ways in which a gradual increase in an extra cellular signal gives a threshold response. So if we were to have a little graph of the response is a response on so wise response and excess concentration, we would have no response, no response, no response and then suddenly, response like so that's that's what that's for the responsible looking for. So how are we going to get that? Well, let's describe three ways. First of all, is if your receptor requires multiple effective fuels, receptor needs well, inspector molecules, and what this does is it makes it more reliant on concentration. If there's a low concentration, you may only have a single effect, sir, but as you increase concentration, you get more about defectors and this This sharpens for response. This steepens This response here, right? Right two is if the effect er both activates one enzyme and inhibits the opposite enzyme. So the effect er activates the forward reaction, let's say and inhibits the reverse reaction is a way of putting it so if there's, say, a protein kinase and protein prosperity's, perhaps your effect activates bikinis and inhibits with hospitals, which again sharpens response because you're preventing for reverse reaction. And finally, the final way of getting this very sharp curve is to have positive feedback groups. She wants to put positive feedback loops in the signaling pathways, so the effect of binds and the response begins in every state. In response, you then go back and reactivate a response which is very commonly found. If we need this all or nothing response.

The experiment of dairy in person and person short that be step patterns. Get this step Children that higher, read or hydrate. This process was linked with the rigidity four gene expression, which is linked with the Darwinian framework. Darwinian dream Work off Natural selection Natural selection darling in Fremaux Cough Natural selection.

Here, we're going to describe the mechanism for a home in response for an interest cellular hormone receptor. He's a relatively wrap if I give a couple examples of Bayreuth elements and we have several months. Both use intracellular receptions, but what happens? Well, the hormone must be capable of passing through, remembering it diffuses remembering diffusion into the cell, and then it binds to receptors, as he expects on this receptor. It could be in this article, or it could be a cell nucleus. But what happens next is the woman or SEPTA complex binds to DNA on, and this initiates transcription initiates transcript. And that means that you get up regulation of the protein synthesis for that particular gene, and that protein carries out the hormonal response, whatever it may be.


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