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A baby is born with a condition where they have too much collagen in proportion to the amount of hydroxypatite. Describe how this affects the quality of their bone...

Question

A baby is born with a condition where they have too much collagen in proportion to the amount of hydroxypatite. Describe how this affects the quality of their bone

a baby is born with a condition where they have too much collagen in proportion to the amount of hydroxypatite. Describe how this affects the quality of their bone



Answers

An X-ray of the right femur in a child shows that it is shorter than the opposite femur, and below the average length for a child of this age. Which region of the bone is most likely to have caused this abnormality? (A) Diaphysis (B) Metaphysis (C) Epiphysis (D) Periosteum

Scurvy causes calls introduction to be intimidated, lack of fruits and vegetables. As a result, the paradox of like minutes to complete and in the teeth fall out.

This question asks us to hypothesize what might happen to a women's bones if she did not increase your intake of calcium during pregnancy. So we know that bones have a lot of different functions, and specifically they have an ability to store calcium and phosphorus so they act as a reservoir for calcium phosphorus, and let's actually write that down so they are able to maintain home your Stasis specifically in terms of blood calcium level by either releasing calcium from bones or storing the calcium in bone tissue. So if blood calcium is low, then we have calcium is released from the bones. But this becomes a problem if our pregnant woman does not have enough calcium or does not take calcium supplements during pregnancy, because the fetus will need to have a lot of calcium to develop their bones. And if we are lacking calcium, then the calcium will start coming from the mother's bones, which could lead to osteoporosis, where there is going to be a decrease in bone density because this calcium has been transferred from the bones into the blood. So this is why it's important

So this question is asking why a person with a vitamin D deficiency would have fragile bones. Um, so calcium cannot be absorbed in the intestines without vitamin D. Um, and without vitamin D, there would be the little to no calcium intake, which would equal, um, a low bone density. And this would present as brittle bones. Um so it is important to consume not only just calcium but also to consume byte of India's well to help stimulate the absorption of calcium.

So this question is all about collagen. First, what's answer? What is collagen? So collagen is the most abundant fibrous protein in connective tissue, and it is one of the main proteins that's going to make up the extra cellular matrix. And its basic structure is that it's made out of three poly peptides called Alfa chains that twist into a collage Ernest Triple helix. And let's talk about how it was synthesised so. Pro collagen, a precursor to collagen, is synthesized and secreted by fibroblasts in the exercise of their matrix. And once it's secreted, we have some extra cellular peptide aces that remove the end and C terminal pro peptides to form functional collagen. And the next part of this question is asking us, How do we know that collagen is required for a tissue integrity? So an example that the textbook gives us is scurvy, which is this disease that you get if you don't consume enough vitamin C. That was really common historically in sailors and in what essentially happens in the scurvy is that cells are deprived of a score bait, and without that, pro collagen is not able to assemble into structural Colijn in the effects of not having enough collagen in the body are that the blood vessels that tendons and skin become fragile without that structural support. And so that is telling us that the collagen is vital for these tissues to retain their shape and their strength.


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