Okay, So in this one, we're looking at Clostridium difficile. Now, this is a infection that occurs in a, um, human bio, the gut. And so whenever we're answering questions, where do we start? How do we answer any question? Well, we need to know what the questions asking. So after reading it, the question here is at the bottom. It says, Why do you suppose microbiota transplantation is so effective? So it was to know what's going on when we do a transplantation of microbiota that makes it effective in this particular case right here. So we're talking about again a human gut infection from a specific bacteria, and it So what do we need to do? So, like I said, we we've figured out what the questions asking us. And now we need to filter out and useful or bad information, uh, and also determine what the question is telling us kind of what clues isn't giving us. So here, um it tells us the leading cause of hospital associate ID. Gastrointestinal illness. That's that's background information. That's not something that's going to help us answer this question necessarily, um, typically treated with a course of antibiotics, but it Rikers in about 20% of cases. Ah, and there difficult to eradicate because the existence of the two forms of bacteria. So while this is not directly important, it does tell us what we need to be looking for When were either researching this or looking back through the are notes. So we have two different forms. One of them is susceptible to antibiotics. The other one is not. It is resistant to antibiotics. So the fact that part of this species of bacteria is, uh, resistance to antibiotic in one form kind of tells us why this particular infection can become so aggressive. So then it goes on to tell us that microbiota transplantation on, then tells us what that ISS I can't resolve over 90% of recurrent affection. So basically, once these infections start recurring, this new experimental treatment, um, is very effective and curbing it, whereas antibiotics tend to actually make it worse. And so we're gonna go into that here just second. So what do we have going on? So we need to go back and figure out what words we don't know. Like microbiota. What is Microbiota? Microbiota is microorganisms of a particular habitat site or geological period. Now, we're not talking about geologic time here. We're talking about the human gut. So the habitat or site of this microbiota is our got in the microorganisms that exist in it. Okay, so was simple fight. Let's look at what the gut looks like in terms of ah Microbiome of microbiota, if you will. So in our gut would got we're going to simplify this. We've got three their friend bacteria that exists. Okay, so in this case, X is gonna be our Clostridium difficile. This is the one that exist in two different forms, but in this case, we're just gonna leave it as the next. All right? So a lot of times, what happens is is you get an infection somewhere else in the body and your doctor prescribes you a antibiotics. In this case, we're gonna represent the antibiotics, is a square, you take the antibiotics, and what happens is is while it treats the infection that you have, it also effects your microbiome in your gut, and it can kill off these other bacteria. So what happens is you're left with an over abundance of the Clostridium difficile. Now in this case. You know, all of a sudden you have this gut infection and you go back to the doctor, and their next answer is Oh, well, you've got an infection. We should probably give you some more antibiotics. So they give you another course of antibiotics, kills off some of it. But again, because some of these, um, sports sport form of this bacteria are resistant to antibiotics were left again with an over abundance of this same bacteria and such. The infection continues. So what do we need to do here? Well, obviously, antibiotics are not the answer, so we don't want any more antibiotics. So what do we want to do? Well, at this point, because we have this doctors have figured out Well, what if we took normal, healthy bacteria and reintroduced the back end? Okay. And this is where the fecal microbiota transplantation comes in. So we go into the hospital. Our gut looks like this. The doctors say Okay, we're gonna introduce this bacteria and this bacteria back to your gut. So these come in. And like with any living organism, you need nutrients. You need things that help you survive. Nutrients, vitamins, minerals, water, What have you to survive? So by reintroducing the selfie bacteria creates a competition for those nutrients, and it kills off some of that bacteria. So now, with having the transpoint of this healthy gut bacteria right here, it reduces the effect on the number of the cost Iridium, the fissile. And so now we have a healthy gut bio magainin without the use of any more antibiotics.