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0 For Small 7 | 7H Pox Seleese all that diseases Ilidde Koch postulates NOT help identifying the causal...

Question

0 For Small 7 | 7H Pox Seleese all that diseases Ilidde Koch postulates NOT help identifying the causal

0 For Small 7 | 7H Pox Seleese all that diseases Ilidde Koch postulates NOT help identifying the causal



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Place the following steps in the correct order, according to Koch's postulates: I. Determine if pure cultures of bacteria cause disease symptoms when introduced to a healthy host. II. Determine if disease symptoms correlate with presence of a suspected pathogen. III. Isolate the suspected pathogen and grow it in pure culture, free of other possible pathogens. IV. Attempt to isolate pathogen from second-infected hosts. a. II, III, IV, I b. II, IV, III, I c. III, II, I, IV d. $\mathrm{II}, \mathrm{III}, \mathrm{I}, \mathrm{IV}$ e. I, II, III, IV

Things, question asks. Which of the following is a pathogen that could not be identified by the provisional coach? Postulates. So we have Staphylococcus aureus, Pseudomonas Eric, you know, Sir Human immune of immunodeficiency virus or HIV and Salmonella and Cherica Serve or tiffin Miriam. So if we look back at our reading, we would find that Choices A, B and E R. All pathogens that could be identified using Coke's original postulates so we can rule out choices A, B and D leaving us with choice. See. And this is also really interesting because we see that the fill a caucus, pseudomonas and salmonella all are going to be categorized as bacteria, whereas our HIV is obviously the virus, so choice see, human immunodeficiency virus is going to be our correct answer.

This'll question. A microbiologist has identified a new gram negative pathogen that causes liver disease in rats. She suspects that the bacterium cimri eight are a violence factor. Describe how molecular coax postulates could be used to test this hypothesis. So here we have our molecular coax postulates listed out, and there are three of them. So we are hypothesizing that the Dembri are going to be a violence factor, and that is going to be our hypothesis. So to test this hypothesis, we have to look at the three Cokes posthumous and proposed three experimental ways to test for the possible. So the 1st 1 would be to test to see if the February or the FINA type is associate ID Onley with pathogenic strains of the species. So it would be important to look at the, um, packages in the ah, in the host. So in this case, it would be the liver of the rats. So to test the 1st 1 we have to look at liver cells and find if the bacteria we're determined. If the bacteria have these February for the second part, which was, ah has to do with the inactivation of the suspected genes associated with pathogenesis ity should result in immeasurable loss of pathogenesis e. So in this case, we should try to, um genetically engineer. These sells these bacterial cells not to have were expressed Embry eight and then determine if it is still pathogenic. And finally, to test the third postulate reversion of the inactive gene should restore the disease unified. So then we could basically use our genetically engineered bacteria and reinstate Dembri observe pathogenesis ity. Will it be pathogenic in this case? So if we conduct this kind of experiment, we will be able to determine if the February are a violence factor.

Robert Costa him with four postulates to support his one microbe, one disease theory.

In the late 18 hundreds, a German scientist in Robert Coke postulated four part theory or kind of procedure on how to link a bacteria to a specific disease. And this brought a lot more clarity to a crazy kind of situation in Europe at that time with disease. And this postulate has four parts, and I'm gonna break it down each part. Anybody's a code to be easy for writing. This red circle means the bacteria were pathogen that we're talking about. So the 1st 1 part one is that the bacteria with pathogen present in all disease cases so that offer some straight across the board. It's president, all disease cases. So we know that's president All cases. Another thing we need to know didn't link it to disease is you gotta be able to grow the bacteria isolated and grow it into appear culture. So I'm gonna write, must be isolated and grown. Pierre and I continued by any other types of bacteria that could cause, um not confidence in the results of this is the one that's leading to the disease so growing pure and then third, a pure culture, that same pathogen, pure culture of our bacteria. If you add that to a healthy person, so unknown endanger individual. It's a healthy person. If you infected with the disease or if you infected with the pathogen, then you get the same disease. And then lastly, um, you've got to be able to extract the same bacteria from experimentally infected person like we're just talking about in part three. So in experimentally experimentally infected person when that was challenged with the bacteria, as we got to call it experience until the infected person has to yield the same bacteria saying So that means our answer for this problem, the only one that's actually part of the postulates, is a


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