## Question

###### The first step in the biological degradation of lysine is reductive amination with $\alpha$ -ketoglutarate to give saccharopine. Nicotinamide adenine dinucleotide phosphate (NADPH), a relative of NADH, is the reducing agent. Show the mechanism.

The first step in the biological degradation of lysine is reductive amination with $\alpha$ -ketoglutarate to give saccharopine. Nicotinamide adenine dinucleotide phosphate (NADPH), a relative of NADH, is the reducing agent. Show the mechanism.

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